Quantitative and qualitative changes of mitochondria in human preimplantation embryos
نویسندگان
چکیده
منابع مشابه
Ultrastructural changes in preimplantation rabbit embryos.
Follicular oocytes and penetrated eggs of several mammalian species have been the subject of numerous electron microscope studies (rat: Sotelo 1959, Sotelo and Porter 1959, Franchi 1960, Odor and Renninger 1960, Szollosi and Ris 1961, Guinea pig: Anderson and Beams 1960, Adams and Hertwig 1964, Austin 1965. Barron and Franklin 1968. cat: Liss 1964. man: Stegner and Waternberg 1961, Zamboni et a...
متن کاملI-13: Transcriptome Dynamics of Human and Mouse Preimplantation Embryos Revealed by Single Cell RNA-Sequencing
Background: Mammalian preimplantation development is a complex process involving dramatic changes in the transcriptional architecture. However, it is still unclear about the crucial transcriptional network and key hub genes that regulate the proceeding of preimplantation embryos. Materials and Methods: Through single-cell RNAsequencing (RNA-seq) of both human and mouse preimplantation embryos, ...
متن کاملIntracellular pH regulation in human preimplantation embryos.
We report here that intracellular pH (pH(i)) in cleavage-stage human embryos (2-8-cell) is regulated by at least two mechanisms: the HCO(3)(-)/Cl(-) exchanger (relieves alkalosis) and the Na(+)/H(+) antiporter (relieves acidosis). The mean pH(i) of cleavage-stage embryos was 7.12 +/- 0.008 (n = 199) with little variation between different stages. Embryos demonstrated robust recovery from alkalo...
متن کاملMitochondria and human preimplantation embryo development.
Human reproduction, like all biological systems, is characterised by a large level of variability. In this field, the variability is observed as a large difference in implantation potential of human embryos developing in vitro, despite similarities in observable parameters such as rate of development and morphology of these embryos. One of the underlying factors that determines developmental po...
متن کاملChanges in responsiveness of preimplantation mouse embryos to serum.
Changes in uptake of radioactive uridine and its incorporation into RNA were determined in preimplantation mouse embryos, from the 2-cell to the blastocyst stage, as a measure of their responsiveness to extracellular conditions. Two media were tested, one contained serum and the other contained bovine serum albumen as a control. An increase in the acid-soluble pool occurred at the 8-cell stage ...
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ژورنال
عنوان ژورنال: Journal of Assisted Reproduction and Genetics
سال: 2017
ISSN: 1058-0468,1573-7330
DOI: 10.1007/s10815-017-0886-6